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XIO2001: xio2001 missing in high temp.

Part Number: XIO2001

Dear sir, 

we have encountered a xio2001 bridge missing in 40~50C temp and the issue can be duplicated in power cycling testing(code reboot). the fail rate is about 80%. if the bridge is missing,  there is no way to get recover even warm reboot . please help us to review schematic and give any suggestion. Ge-XIO-2.pdf