MAX3221: May I have some confirming item for MAX3221CPWR application ?

Dear SIR:

Good day!! 

May I have some question regarding MAX3221CPWR as below question ?

(1)MAX3221CPWR  pin3 (V+)  how to connect ? (for example 1 and 2 ,which one is correct ? or ,....)

    (for example 1: MAX3221CPWR  pin3 (V+) through a 0.1uf  cap. connect to  +3.3V )

     (for example 2: MAX3221CPWR  pin3 (V+) through a 0.1uf  cap. connect to  GND )

(2) as above for example 1 and 2 ,Have any different for application or consider,if both are correct ?)  

(3)"MAX3221CPWR can replace  MAX3243ECDBR" and " MAX3243ECDBR can replace MAX3221CPWR" ?

     (change another word:"Original circuit use MAX3221CPWR can directly change to MAX3243ECDBR    ,drop in capable  ?"

                                   and "Original circuit use MAX3243ECDBRR can directly change to MAX3221CPWR    ,drop in capable  ?" )

(4)Have any application different between MAX3243ECDBR  and MAX3243ECDBR ?

    (change another word: what's condition necessary use MAX3243ECDBR and   what's condition necessary use  MAX3243ECDBR ? )

 Thanks