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SN65DSI86-Q1: Does it matter for a landscape mode or portrait mode panel?

Part Number: SN65DSI86-Q1
Other Parts Discussed in Thread: SN65DSI86

Hi

I knew from the datasheet that SN65DSI86 can support WQXGA resolution@60HZ.

But does it matter for the panel design is in landscape mode(2560RGB*1600) or in portrait mode(1600RGB*2560)?