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SN74AXC1T45: SN74AXC1T45 can shift 2.5V signal to 1.8V, but not shift 1.8V signal to 2.5V

Part Number: SN74AXC1T45

As the below PIC

D0_2V5 on U2-PIN3 can be shifted to U2-PIN4 as D0_1V8
but
D1_1V8 on U3-PIN4 can not be shited to U3-PIN3 as D1_2V5

Debug @:
1, inpedance of U2-PIN3/PIN4 and U3-PIN3/PIN4 is about 42K ohm
2, diode characteristic of U2/U3-PIN1/3/4/6 is about 0.45V

so, any suggestion to debug ? thanks

Wang