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AM4378: How to load application with out loading OS

Part Number: AM4378

Is this possible if i want to make my application load from Non-Volatile memory  directly with out having any OS dependency as our customer application is based on Simple serial protocol based . If possible can some direct us how to implement. Sorry if my question is wrong as i too bit confused while putting this question. With out OS is it possible to load the application  directly to Processor(Confused then how to implement serial interfaces).

Current we are using AM4378 custom board with Processor SDK 04.02 to build OS.

Thanks & Regards

A.N.V.Lavanya