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SN74CBTLV3125 - I/O Speed

Other Parts Discussed in Thread: SN74CBTLV3125

We are using SN74CBTLV3125 switch for isolation purpose. Buffer is powered by 3.3V but the signal we are transferring is 1.8V.

1. I like to confirmation on the VCC voltage (3.3V) doesn't have an impact on the I/O data signal switching ?

2. what is the maximum speed  this switch will support on the I/O signal transfer ?

Thanks