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OPA348: Abnormal offset from the output of the amplifier

Part Number: OPA348
Other Parts Discussed in Thread: TL072

Hello

I see a abnormal offset from the output of the ADC.

I use a non-invert input amplifier to amplifier the signal. The input signal is 1.5V bias + 0.00085V(peak) sin wave, 50Hz

In the output, I see a strange offset. It seems the offset changes when the signal cross 1.5V. When the signal is higher than 1.5V, the offset is positive. When the signal is less than 1.5V, the offset is negative.

But in simulation, I could not see this.

Could you help explain why and how to solve this problem?