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SN74AVC4T245: PORT-A/B

Part Number: SN74AVC4T245
Other Parts Discussed in Thread: TXU0204

Tool/software:

According to the following schematic from the SN74AVC4T245 datasheet, is there any problem if I change the power supply VCCB to 1.8V and VCCA to 3.3? Respecting that the direction would change from B to A inputs. And P1DIR will be connected to GND and P2DIR to 3.3V.