Other Parts Discussed in Thread: TINA-TI
it looks like the SN74LVC2G241 spice model doesn't model the High-Z condition correctly, but just connects the output hard to GND when the output is disabled. But I'm paticulary interested to simulate the output when it is disabled.
Attached is a simple Tina-TI file for reference. I connected a pullup to the output, and the output is low when the output is disabled. When the output is enabled, it works as expected.