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TPS2557: TPS2557

Part Number: TPS2557

I would like to know what happens if 5 volts is present ( in our case  from a usb port ) on the 2 out pins of this device.   EN will be set low, but what if the out pin(s) are at 5 volts before power on the IN pins is on.  can the out pins back feed the in pins?  the scenario is a usb cable is attached to our product and the product is not powered on.