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AM6442: AM64x power supply and compatibility

Part Number: AM6442
Other Parts Discussed in Thread: AM6421

Hello, I have questions about AM64x.

Question 1:
AM64x VDD_CORE can be selected from 0.75 or 0.85V. Is this determined by the model number? Could you tell me the difference between them?

Question 2:
VDDS_DDR can be selected from 1.1 or 1.2V. Is this determined by the DDR used?
DDR4:1.2V
LPDDR4:1.1V

Question 3:
Is it possible to replace the AM64x series without change because it is pin compatible?
My customers designing with AM6442 are considering  and replace it with AM6421.

Regards,
Rei