TMUX4052-Q1: ISO7637 5b test

The absolute maximum ratings allow a diode clamp current of at most 30 mA.

You need external protection.

You should limit the current through the 4052's clamping diode to much less than 30 mA. So if you use a current-limiting series resistor, its resistance should be more than (36 V − V_CC) / 30 mA.

Yes, the current-limiting resistor will prevent the TMUX4052-Q1 itself from being damaged. Your circuit still needs to be able to handle the current flowing into V_CC. (If the V_CC voltage floats up, all devices connected to it might get damaged.)

There are diodes between the I/O pins and the supply rails. If you apply any voltage more than 0.5 V beyond the rails, a current will flow, and the diodes will clamp the voltage to their own forward voltage.

You could add external diodes in parallel with the internal ones. (Use a resistor between the external diode and the pin so that most of the current flows through the external one.) You can size these external diodes for whatever current is needed.

When there is a high voltage at z02.CC1/2, then a current flows through R9733, and the voltage drop over R9733 will make the voltage at the chip's pin higher than the supply voltage (z02.U140P_USB3).

Drop that resistor, and add series resistors between the pins (DB and S0A) and the diodes.

(And VDD needs a low-impedance connection to the supply; remove R9730.)

The only way to prevent high voltages from reaching the chip is to put resistors between the high-voltage inputs and the chip:

Vdd high voltage problem we will use another stable power.  For I/O pin I mean you suggest series resister on CC1/CC2 pin for limit current, but we can't do that, we add schottky diode to prevent CC1/CC2 voltage from exceeding Vdd and prevent current from passing through