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CC2564C: How to connect CC2564C UART when debug with HCI Tester Tool

Part Number: CC2564C

Hi

1. In order to debug by HCI tester tool, Connect 4-wire UART according above picture. Tx, Rx, CTS and RTS.

Because CC2564C UART output is 1.8V, is it must add a level shift between CC2564C and hoster?  Is there any more pin need to be connected?

2. There is no level shift on hand, so we try to connect it by 3-wire UART, Tx, Rx and GND.  

I can see the signal send out from Host, but no response from CC2564C, Is there any connection error? Thanks.