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AMC1301-Q1: AMC1301-Q1 isolate analog signal,

Part Number: AMC1301-Q1
Other Parts Discussed in Thread: AMC1301, ISO124

I want to use AMC1301-Q1 to  isolate analog signal.The input range  of AMC1301-Q1 is ±250mV,and fixed-gain is 8.2.  But table 6.1 indicate the range of  VINP   is  (GND1-6) to (VDD1+0.5). Please help me if I can use it  to  isolate analog signal with the  frequency if 10kHz,amplitude is  5V,and   not difference???