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SN65LVPE512: SN65LVPE512 problem

Part Number: SN65LVPE512
Other Parts Discussed in Thread: TUSB522P, SN65LVPE502A, TUSB7340,

Hi, we are currently using  the LVPE512 part on multiple legacy systems. About in this year, we plan to put two or more LVPE512 parts in cascade in a new design very soon, so can we do it? If not, why? What if we use the new TUSB522P part? 

I saw Moises Garcia replied to Dror, "We had seen some interoperability issues with LVPE512 and placing them in cascade was not possible.TUSB522P is an improved version of LVPE512, it fully supports USB3.1 Gen1(5 Gbps)" 

We would like to have answers from TI by a 1st week of May 2018 we are appreciated. Waiting for a reply.