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CD4541B: CD4541B-E3 VS CD4541B-E4

Part Number: CD4541B

Dear Ti Expert,

Is any difference in terms of functionality between CD4541B-E3 and CD4541B-E4. Can we use CD4541B-E3 as a replacement for CD4541B-E4?    The reason I am asking this is because our design normal use CD4541B-E4 for production, and the system operates as expected. However, when we changed the part to CD4541B-E3, the system exhibits instability. The system returns to normal again once we switched the device back to CD4541B-E4. We really don't know why the system behave like that?

Best regards,

Peter