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CDCM6208V1F: This Device can not be locked

Part Number: CDCM6208V1F
Other Parts Discussed in Thread: CDCM6208

Hi Dear

The configuration of the device CDCM6208V1F  is:

reg0: 01B9

reg1: 000C

reg2: 0017

reg3: 10F0

reg4: 234D

reg5: 01BB

reg6: 0002

reg7: 0023

reg8: 0005

reg9: 0003

reg10: 0050

reg11: 0000

reg12: 0003

reg13:0050

reg14:0000

reg15:00D3

reg16:0170

reg17:0000

reg18:00D3

reg19:0170

reg20:0000

My whole design is like the following picture:

register0~20 reading value is the same with the value I want to write.

But reg21.1 = 1 which means Loss of ireference input. I use an active crystal as the refference input, frequency is 100MHz, 3.3V LVDS and I'm sure that the crystal is ok.

Could you please help me analysis this issue?  Is the configuration right?